Characterization of envelope proteins of alcelaphine herpesvirus 1
نویسندگان
چکیده
منابع مشابه
Preliminary characterization of the alcelaphine herpesvirus 1 genome.
Alcelaphine herpesvirus type 1 (AHV-1) is a causative agent of the fatal lymphoproliferative disease malignant catarrhal fever in deer and cattle. The genomes of the attenuated WC11 isolate and the virulent C500 isolate have been studied. The genome of WC11 comprises a region of unique DNA of approximately 130 kbp, which has a G + C content of 50%, and approximately 30 kbp of additional tandem ...
متن کاملProteomic analysis of pathogenic and attenuated alcelaphine herpesvirus 1.
The gammaherpesvirus alcelaphine herpesvirus 1 (AlHV-1) causes malignant catarrhal fever in susceptible ungulates but infects its natural host, wildebeest, without obvious clinical signs. In tissue culture, AlHV-1 is initially predominantly cell associated and virulent but on extended culture becomes cell-free and attenuated. We wanted to determine what changes in protein composition had taken ...
متن کاملPrimary structure of the alcelaphine herpesvirus 1 genome.
Alcelaphine herpesvirus 1 (AHV-1) causes wildebeest-associated malignant catarrhal fever, a lymphoproliferative syndrome in ungulate species other than the natural host. Based on biological properties and limited structural data, it has been classified as a member of the genus Rhadinovirus of the subfamily Gammaherpes-virinae. Here, we report on cloning and structural analysis of the complete g...
متن کاملAlcelaphine herpesvirus type 1 has a semaphorin-like gene.
Alcelaphine herpesvirus type 1, a rhadinovirus causing malignant catarrhal fever of ruminants, has an 1959 nucleotide open reading frame with significant homologies to semaphorin genes. While truncated genes of similar structure have been found in poxviruses, this is the first known example of a semaphorin-like gene in a herpesvirus.
متن کاملEx vivo bioluminescence detection of alcelaphine herpesvirus 1 infection during malignant catarrhal fever.
Alcelaphine herpesvirus 1 (AlHV-1), carried by wildebeest asymptomatically, causes malignant catarrhal fever (WD-MCF) when cross-species transmitted to a variety of susceptible species of the Artiodactyla order. Experimentally, WD-MCF can be reproduced in rabbits. WD-MCF is described as a combination of lymphoproliferation and degenerative lesions in virtually all organs and is caused by unknow...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Virology
سال: 1990
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.64.7.3382-3390.1990